Earlier this month, the United States imposed its own sanctions on Saudi officials for the same reason.
"I must note we are seldom free to work with unblemished partners.Our security interests can not be dismissed, even as we seek accountability for what President Trump described as the "unacceptable and frightful crime" of Jamal Khashoggi's murder", Mr Mattis said, according to remarks sent to reporters.
He told Al Arabiya News Channel in the presence of Crown Prince Muhammad Bin Salman that the relations between the two countries are historical.
Freeland said a credible and independent global investigation needs to happen.
"This case is not closed as far as Canada is concerned", Freeland said. "These are not accusations that we can make lightly".
He was met with protests in Buenos Aires and the summit is expected to create tensions between the prince and Western leaders.
But he also said that the killing of Khashoggi would be discussed in the meeting.
CIA Director Gina Haspel, who has listened to an audio tape of the killing and reviewed evidence assembled by Turkish authorities, did not participate in the briefing despite senators demands to hear directly from her.
Mueller: Plea Deal 'Breached' by Manafort Lying to FBI, Special Counsel
Manafort's case means, at a minimum, that prosecutors will not ask for a lighter punishment in return for his cooperation. He was found guilty on eight counts , including tax fraud, money laundering and lying to the government.
She said that Canadian security officials have been in direct contact with Turkey regarding its investigation, information has been shared, and that the director of the Canadian Security Intelligence Service has been to Turkey.
Warren's letters to the remaining five firms seek confirmation of reports that those companies have severed ties with the desert kingdom following Khashoggi's murder. But Canada hasn't cancelled a multibillion-dollar military armored vehicle contract. It may yet be significantly amended, it would not stop arms sales to Saudi Arabia or the United Arab Emirates, and would face an uphill challenge to be passed by the House of Representatives.
On Wednesday a source said that the court had accepted the writ, and a prosecutor had asked a judge to determine if either Saudi Arabia or Yemen are investigating the prince for possible crimes against humanity.
They said the meeting signifies the importance that both leaders attach to the issue of climate change.
People hold signs during a protest at the Embassy of Saudi Arabia about the disappearance of Saudi journalist Jamal Khashoggi, in Washington.
Former Secretary of State Hillary Clinton has suggested that U.S. President Donald Trump is "part of the cover-up as to what happened" in the murder of Saudi journalist Jamal Khashoggi.
ALEX EDELMAN/UPI/NewscomFinally a bit of bipartisanship with merit: Senators yesterday made a decision to at least debate ending US sponsorship of Saudi Arabia's aggression in Yemen.